AOR
Archives of Ophthalmological Research

The Archives of Ophthalmological Research aims to publish issues related to publish articles of the highest scientific and clinical value at an international level, and accepts articles on these topics. The target audience of the journal included specialists and physicians working in ophthalmology, and other health professionals interested in these fields.

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Original Article
Regional histopathologic differences between nasal and temporal upper eyelid tissues in blepharoplasty specimens
Abstract
Aims: To investigate histopathologic differences between the nasal and temporal portions of upper eyelid blepharoplasty specimens in dermatochalasis.
Methods: This retrospective observational study included 82 eyes with available nasal and temporal upper eyelid excision specimens. The number of dilated lymphatic vessels, maximum lymphatic vessel diameter, elastic fiber count, macrophage count, and capillary count were evaluated separately in both regions. Paired comparisons were performed using the paired-samples t-test or Wilcoxon signed-rank test, as appropriate.
Results: The study included 82 eyes from 41 patients. The mean age was 59.1 ± 8.56 years; 26 patients (63.4%) were female and 15 (36.6%) were male. The nasal region showed significantly higher values for dilated lymphatic vessel count (6.99±1.79 vs 6.51±1.36; p<0.001), elastic fiber count (3.32±0.93 vs 3.06±0.91; p=0.003), and capillary count (13.46±3.14 vs 12.84±3.25; p<0.001). No significant differences were found for maximum lymphatic vessel diameter (239.29±57.71 µm vs 242.05±59.49 µm; p=0.228) or macrophage count (26.67±2.70 vs 26.40±2.63; p=0.101).
Conclusion: Regional histopathologic differences were observed between the nasal and temporal portions of upper eyelid blepharoplasty specimens. The nasal region showed higher counts of dilated lymphatic vessels, elastic fibers, and capillaries than the temporal region.

Keywords : Dermatochalasis, blepharoplasty, upper eyelid, histopathology, lymphatic vessels, elastic fibers

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Article available in :
Volume 3, Issue 3, 2026
Page : 57-60
https://doi.org/10.51271/AOR-0057
Article Information
Received : 12 Aug 2026
Accepted : 21 Sep 2026
Published : 24 Sep 2026
Corresponding Author :

Elmas Yüksel Şükün: Department of Ophthalmology, Alanya Training and Research Hospital, Antalya, Turkiye

[email protected]
Citation : Yüksel Şükün E, Sipahioğlu S, Çiçekdağı I. Regional histopathologic differences between nasal and temporal upper eyelid tissues in blepharoplasty specimens. Arch Ophthalmol Res. 2026;3(3):57-60. doi:10.51271/AOR-0057

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